The homogeneity test of annual mean temperature series is carried out using annual mean temperature over Shandong Province from 1961 to 2005 by means of the regressive method. Through the contrastive analysis of the historical information about meteorological station, it is found that the regressive method can be applied to the homogeneity test on the annual mean temperature series with the significance level being 0.01. The results show that the relocation, environment, observational instrument type or observation time of stations have direct effects on the continuity of observational records and the homogeneity of climatological data. Especially, the change of observation station location is the most important factor.