The scheme of the high precision temperature and humidity intelligent sensor system is determined through analyzing the functional requirements for the meteorological data acquisition system. The overall scheme and the realization of hardware and software systems are introduced. To realize the functions of high accuracy measurement, automatic collection, and real time processing, based on the CAN Bus, the main control chip LPC1768 is selected, in combination with the low power consumption architecture of ARM CORTEX M3, 16 bit serial A/D conversion chip AD7792 with low power consumption, and the high speed CAN transceiver SN65HVD230 with low power consumption. Compared with the existing meteorological data acquisition equipment, it has the characteristics of smaller size, lower power consumption, flexible networking, and higher measuring precision. The test results show that the high precision intelligent sensor is stable, reliable and has the functions of high precision,self checking, self calibration, and self adaption.