Red cartridge kiwifruit canker disease sees an uptrend in recent years in the western Guizhou as the production scale of red cartridge kiwifruits is extended quickly, and this disease has become one of the main limited factors in the production of red cartridge kiwifruits in this area. Based on the 6year observation data of the main planting areas of red cartridge kiwifruits in the western Guizhou Province, the correlation analysis method is used to study the relationship between meteorological factors and the occurrence of cartridge kiwifruit canker disease. The meteorological factors with better correlation are selected as the prediction factors of red cartridge kiwifruit canker disease. The meteorological prediction model of red cartridge kiwifruit canker disease is established based on the monitoring data of red cartridge kiwifruit canker disease. It is concluded: When the daily average temperature of 5 days or more from midDecember to early January of next year is less than 2 ℃, the daily minimum temperature was less than -2 ℃ and the daily average relative humidity is more than 75%, the canker disease will begin in the early March, with a prediction accuracy of 50%. When the average daily temperature of 5 days or more from midJanuary to late January is less than 2 ℃, the lowest daily temperature is less than -2 ℃ and the average daily relative humidity is more than 75%,the canker disease will begin in the midMarch, with a prediction accuracy of 100%. When the average daily temperature of 5 days or more from early to midFebruary is less than 2 ℃, the lowest daily temperature is less than -2 ℃ and the average daily relative humidity is more than 75%, the canker disease will beginning in late March, with an accuracy of 100%.